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1 or 2 weeks. Usual maintenance dose is 25 to mcg daily. The rapid onset and dissipation of action of liothyronine sodium T3 ; , as compared with levothyroxine sodium T4 ; , has led some clinicians to prefer its use in patients who might be more susceptible to the untoward effects of thyroid medication. However, the wide swings in serum T3 levels that follow its administration and the possibility of more pronounced cardiovascular side effects tend to counterbalance the stated advantages. Cytomel liothyronine sodium ; Tablets may be used in preference to levothyroxine T4 ; during radioisotope scanning procedures, since induction of hypothyroidism in those cases is more abrupt and can be of shorter duration. It may also be preferred when impairment of peripheral conversion of T4 to suspected. Myxedema: Recommended starting dosage is 5 mcg daily. This may be increased by 5 to mcg daily every 1 or 2 weeks. When 25 mcg daily is reached, dosage may be increased by 5 to mcg every 1 or 2 weeks until a satisfactory therapeutic response is attained. Usual maintenance dose is 50 to 100 mcg daily. Myxedema Coma: Myxedema coma is usually precipitated in the hypothyroid patient of long standing by intercurrent illness or drugs such as sedatives and anesthetics and should be considered a medical emergency. An intravenous preparation of liothyronine sodium is marketed by JONES PHARMA INCORPORATED, under the trade name Triostat for use in myxedema coma precoma. Congenital Hypothyroidism: Recommended starting dosage is 5 mcg daily, with a 5 mcg increment every 3 to 4 days until the desired response is achieved. Infants a few months old may require only 20 mcg daily for maintenance. At 1 year, 50 mcg daily may be required. Above 3 years, full adult dosage may be necessary see PRECAUTIONS, Pediatric Use ; . Simple non-toxic ; Goiter: Recommended starting dosage is 5 mcg daily. This dosage may be increased by 5 to mcg daily every 1 or 2 weeks. When 25 mcg daily is reached, dosage may be increased every week or two by 12.5 or 25 mcg. Usual maintenance dosage is 75 mcg daily. In the elderly or in pediatric patients, therapy should be started with 5 mcg daily and increased only by 5 mcg increments at the recommended intervals. When switching a patient to Cytomel liothyronine sodium ; Tablets from thyroid, L-thyroxine or thyroglobulin, discontinue the other medication, initiate Cytomel at a low dosage, and increase gradually according to the patient's response. When selecting a starting dosage, bear in mind that this drug has a rapid onset of action, and that residual effects of the other thyroid preparation may persist for the first several weeks of therapy. Thyroid Suppression Therapy: Administration of thyroid hormone in doses higher than those produced physiologically by the gland results in suppression of the production of endogenous hormone. This is the basis for the thyroid suppression test and is used as an aid in the diagnosis of patients with signs of mild hyperthyroidism in whom baseline laboratory tests appear normal or to demonstrate thyroid gland autonomy in patients with Graves' ophthalmopathy.131 I uptake is determined before and after the.
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ADVERSE REACTIONS Adverse reactions, other than those indicative of hyperthyroidism because of therapeutic overdosage, either initially or during the maintenance period are rare see OVERDOSAGE ; . In rare instances, allergic skin reactions have been reported with Cytomel liothyronine sodium ; Tablets. OVERDOSAGE Signs and Symptoms Headache, irritability, nervousness, sweating, arrhythmia including tachycardia ; , increased bowel motility and menstrual irregularities. Angina pectoris or congestive heart failure may be induced or aggravated. Shock may also develop. Massive overdosage may result in symptoms resembling thyroid storm. Chronic excessive dosage will produce the signs and symptoms of hyperthyroidism. Treatment Of Overdosage Dosage should be reduced or therapy temporarily discontinued if signs and symptoms of overdosage appear. Treatment may be reinstituted at a lower dosage. In normal individuals, normal hypothalamic-pituitary-thyroid axis function is restored in 6 to weeks after thyroid suppression. Treatment of acute massive thyroid hormone overdosage is aimed at reducing gastrointestinal absorption of the drugs and counteracting central and peripheral effects, mainly those of increased sympathetic activity. Vomiting may be induced initially if further gastrointestinal absorption can reasonably be prevented and barring contraindications such as coma, convulsions, or loss of the gagging reflex. Treatment is symptomatic and supportive. Oxygen may be administered and ventilation maintained. Cardiac glycosides may be indicated if congestive heart failure develops. Measures to control fever, hypoglycemia, or fluid loss should be instituted if needed. Antiadrenergic agents, particularly propranolol, have been used advantageously in the treatment of increased sympathetic activity. Propranolol may be administered intravenously at a dosage of 1 to mg over a 10-minute period or orally, 80 to 160 mg day, especially when no contraindications exist for its use and lomefloxacin.
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Pharyngitis cont'd ; Acute Group A Streptococci Penicillin VK Alternative Erythromycin or Clindamycin 40mg kg d PO div bid 40mg kg d PO div tid 20mg kg d PO div tid 10 days * 10 days * 10 days * * No good evidence that shorter courses of antibiotic therapy including cephalosporins, azithromycin, clarithromycin ; are as effective as 10 days. - If treated empirically NOT recommended ; , & 48 hour throat swab culture is negative, discontinue antibiotics. * Consider: noncompliance concurrent viral infection in a Group A Strep carrier suppurative complication of Group A Strep pharyngitis e.g. peritonsillar, tonsillar, and retropharyngeal abscess ; . Early relapse: repeat throat swab necessary only treat if culture positive for Group A Strep. - Group A Strep resistance to macrolides and clindamycin is increasing.
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Tion, the M184V mutation was not detected in any of the 22 successfully amplified case samples of 50 samples available ; . In S1 and S2 case samples, the only primary resistance mutation detected in the reverse transcriptase gene was the M184V substitution, present in most patients receiving a lamivudinecontaining maintenance regimen TABLE 1 ; . The key codon 215 zidovudine resistance mutation was not detected. Two patients developed minor codon 41 or 70 zidovudine resistance mutations. In comparison with baseline data, the protease genotype in S1 and S2 samples showed only secondary indinavirassociated mutations, and in only 7 patients, 4 of whom were in the zidovudine-lamivudine maintenance arm.13 A set of 4 secondary mutations codons 20, 36, 71, and 77 ; was found in sample S2 from 1 case in the triple-drug maintenance arm; these can be selected before the primary mutations at codon 46 or 82, conferring resistance to indinavir.14 There were 22 S1 and 21 S2 samples available from zidovudine-lamivudine controls for M184V testing; of the successfully amplified specimens, the M184V mutation was found in 11 of and in 10 of samples.
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Evolving OS code is hard. It involves extending, integrating, optimizing, re-optimizing, and maintaining system functionality and requires understanding not only the concerns within the system, but their interactions which are inherently complex. Modularity aids evolution by providing structure for comprehensibility and locality of change. It is easier to evolve a system if responsibilities are better separated between concerns. This dissertation shows support for the claim that aspect-oriented programming can be used to improve evolvability in operating system code by providing better modularity. We presented a case study showing improved modularity when three crosscutting concerns in FreeBSD were implemented using AspectC. We also presented a case study showing improved locality of change when the three crosscutting concerns were exposed to change tasks over two evolutionary periods, and showed that improvements in modularity persisted across 3 versions of the system. We inferred from these results that evolution of the aspect-oriented kernels would be easier than the original, due to improved modularity. We then generalized these results to the modularity of more 119.
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Total bile acids are the sum of identified fecal bile acids concentrations. Standards of biliary acids were obtained from Sigma, St. Louis, MO, except the amuricholic and 3-muricholic acid, which were a generous gift of H. Eyssen, Leuven, Belgium. Fecal and cecal pH. At the end of the dietary treatments, before the rats were killed, -100 mg of feces were freshly collected from each rat and homogenized with 2 mL of NaCl with a glassteflon homogenizer. Using a standard pH meter Radi ometer, Copenhagen, Denmark ; with a glass elec trode, pH was immediately determined. Cecal pH was determined in the undiluted cecal contents immediately after killing the animals. Statistical analysis. Data were analyzed with one way ANOVA and linear regression analysis, using Statgrafics Statistical Package Statistical Graphic Corporation, Rockville, MD ; . The differences be tween groups were considered significant at P 0.05 and lotronex.
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Liothyronine t3 ; contains three atoms of iodine and is formed by the coupling of one molecule of diiodotyrosine dit ; unemployment with one molecule - midget wikipedia, of endocrinology: pharmacology: thyroid liothyronine and lovenox.
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Anselin, L. 1990 ; , Estimation Methods for Spatial Autoregressive Structures. Regional Science Dissertation and Monograph Series Nr. 8, Cornell University, Ithaca, New York. Anselin, L. 1988 ; , Spatial Econometrics: Methods and Models, Kluwer Academic Publishers, The Netherlands. Anselin, L.; A. Varga and A. Zoltan 1996 ; , Local Geographic Spillovers Between University Research and High Technology Innovations: A Spatial Econometric Approach. Research Paper No. 9606, Regional Institute and Department of Economics, West Virginia University, Morgantown. Bebbington, A. 1999 ; , "Capitals and Capabilities: A Framework for Analyzing Peasant Viability, Rural Livelihoods and Poverty." World Development 27 12 ; : 202144. Birdsall, N. and J. L. Londoo 1998 ; , "Assets Inequality Matters, " American Economic Review, Papers and Proceedings, May. Deaton, A. 1997 ; , The Analysis of Household Surveys. A Microeconometric Approach to Development Policy. World Bank, The Johns Hopkins University Press, Washington D.C. Engerman, S. L. and K. L. Sokoloff, 1998 ; , "Factor Endowments, Institutions, and Differential Paths of Growth among New World Economies: A View from Economic Historians of the United States?" In: Stephen Haber ed. ; How Latin American Fell Behind: Essays on the Economic Histories of Brazil and Mexico, 1800-1914. Stanford, CA: Stanford University Press. Escobal, J.; J. Saavedra and M. Torero 1998 ; , Los Activos de los Pobres en el Per. Mimeo. Research Report presented to IDB Research Network. Escobal, J. and M. Torero 2000 ; , Does Geography Explain Differences in Economic Growth in Peru? Research Network Working Paper, IDB. Washington D.C. Submitted to the review of Regional Studies, 50. Hardy, A. 1980 ; , "The Role of the Telephone in Economic Development". Telecommunications Policy, 8 1 ; : 23-44. Jalan, J. and M. Ravallion 1998 ; , "Geographic Poverty Traps?" In: Institute for Economic Development Discussion Paper Series, Nr 86, May. Pfeffermann, D. 1993 ; . "The Role of Sampling Weights When Modeling Survey Data". International Statistical Review, 61: 317-337. Ravallion, M. and Q. Wodon 1997 ; , "Poor Areas, Or Only Poor People?" In: Policy Research Working Paper, Nr 1798, World Bank, Washington DC. Saunders, R.; J.J. Warford and B. Wellenius; 1983 ; , "Telecommunications and Economic Development". Second Edition, World Bank, Johns Hopkins University Press, London. Sadoulet, E. and A. de Janvry 1995 ; , Quantitative Development Policy Analysis. Baltimore: Johns Hopkins University Press. Singh, I.; L. Squire and J. Strauss, Eds. 1986 ; , Agricultural Household Models: Extensions, Applications, and Policy. Johns Hopkins University Press for the World Bank, Baltimore and London and lumigan.
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Rimhanen-Finne , R., Ro nkaine n, P., and H annine n, M .L. 20 01 ; Simultaneous detection of Cryptosporidium parvum and Giardia in sewage sludge by ICPCR. J. Appl. Microbiol., 91 6 ; : 10301035. Rimhanen-Finne, R., Horman, A., Ronkainen, P., and Hanninen, M.L. 2002 ; An ICPCR method for detection of Cryptosporidium and Gia rdia in natural surface waters in Finland. J. Microbiol. Meth., 50 3 ; : 299303. Rivera, F., Ramirez, E., B onilla, P ., Calderon, A., Gallegos, E., Rodriguez, S ., Ortiz, R ., Zaldivar, B., Ram irez, P., and Duran, A. 1 993 ; Pathogenic and free-living amoe bae isolated from sw imming pools and physiotherap y tubs in Mexico. Environ. Res., 62 1 ; : 4352. Roach, P.D., Olson, M.E., Whitley, G., and Wallis, P.M. 1993 ; W aterborne Giardia cysts and Cryptosporidium oocysts in the Yukon, Canada. Appl. Environ. Microbiol., 59: 6773. Robertso n, L.J., Camp bell, A.T., and Sm ith, H.V . 199 2 ; Su rvival of Cryptosporidium parvum oocysts under various environmental pressures. Appl. Environ. Microbiol., 58: 34943500. Robertso n, L.J., Camp bell, A.T., and Sm ith, H.V . 199 8 ; V iability of Cryptosporidium parvum oocysts: assessment by the dye permeability assay. Appl. Environ. Microbiol., 64 9 ; : 35443545. Roberts-Thomson, I.C., Stevens, D.P., Mahmoud, A.A.F., and W arren, K.S. 1976 ; Giardiasis in the mouse: an animal model. Gastroenterology, 71: 5761. Rochelle, P.A., Ferguson, D.M., Handojo, T.J., De Leon, R., Stewart, M.H., and Wolfe, R.L. 1997 ; An assay combining cell culture with reverse transcriptase PCR to detect and determine the infectivity of waterborne Cryptosporidium parvum. Appl. Environ. Microbiol., 63: 20292037. Rochelle, P .A., De Leo n, R., Jo hnson, A., Stewart, M .H., and W olfe, R.L. 19 99 ; Evaluation o f immunom agnetic separation for re covery of infectious Cryptosporidium parvum oocysts from environmental samples. Appl. Environ. Microbiol., 65 2 ; : 841845. Rochelle, P.A., Marshall, M.M., Mead, J.R., Johnson, A.M., Korich, D.G., Rosen, J.S., and De Leon, R. 2002 ; Compa rison o f in vitro cell culture and a mouse assay for measuring infectivity of Cryptosporidium parvum. App l. Environ. Microbiol., 68 8 ; : 38093817. Rohr, U., Weber, S., Michel, R., Selenka, F., and Wilhelm, M. 1998 ; Comparison of free-living amoebae in hot water systems of hospitals with isolates from moist sanitary areas by identifying genera and determining temperature tolerance. Appl. Environ. Microbiol., 64 5 ; : 18221824. Rose, J.B ., Haa s, C.N ., and R egli, S. 1991 ; Risk assessment and contro l of waterborne giardiasis. Am. J. P ublic Health, 81: 709713. Rushton, P., Place, B.M., and Lightfoot, N.F. 2000 ; An evaluation of a laser scanning device for the detection of Cryptosporidium parvum in treated water samples. Lett. Appl. Microbiol., 30 4 ; : 303307. Sauch, J.F. 1985 ; Use of immunofluorescence and phase-contrast microscopy for detection and identification of Giardia cysts in water supplies. Appl. Environ. Microbiol., 50: 14341438. Seal, D.V. 2000 ; C ontact-lens-associated microbial keratitis in The Netherlands and Scotland. Lancet, 355 9198 ; : 143 14 4.
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