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Irvine RRA et al: The CAG and GGC microsatellites of the androgen receptor gene are in linkage disequilibrium in men with prostate cancer. Cancer Res 1995; 55: 1937-1940. Isaacs JT: Hormonal balance and the risk of prostatic cancer. Journal of Cellular Biochemistry 16H suppl ; : 107-108, 1992. Iversen P, Tyrrell CJ, Kaisary AV, Anderson JB, Baert L, Tammela T et al. Casodex Bicalutamide ; 150-mg monotherapy compared with castration in patients with previously untreated nonmetastatic prostate cancer. Urology 51: 389-96, 1998. Jaffe JM, Malkowicz SB, Walker AH, MacBride S, Peschel R, Tomaszewski J, et al. Association of SRD5A2 genotype and pathological characteristics of prostate tumors. Cancer Res 2000; 60 6 ; : 1626-30. Jenkins EP, Andersson S, Imperato-McGinley J, Wilson JD, Russell DW. Genetic and pharmacological evidence for more than one human steroid 5 alpha-reductase. J Clin Invest 1992; 89 1 ; : 293-300. Jenkins PJ, Grossman A. The control of the gonadotrophin releasing hormone pulse generator in relation to opioid and nutritional cues. Hum Reprod 1993; 8 Suppl 2 ; : 154-161. Johansson J-E, Andersson S-O, Beckman K-V, Lingrdh G, Zador G. Clinical evaluation of Flutamide and Estramustine as initial treatment for metastatic carcinoma of prostate. Urol 27: 55-9, 1987. Johansson J-E, Andersson S-O, Holmberg L et al. Primary orchiectomy versus estrogen therapy in advanced prostatic cancer - a randomized study: results after 7 to 10 years of followup. J Urol 145: 519-23, 1991. Kaisary AV, Tyrell CJ, Peeling WB et al. Comparison of LHRH analogue Zolodex ; with orchiectomy in patients with metastatic prostatic carcinoma. Br J Urol 67: 502-8, 1991. Kantoff PW, Febbo PG, Giovannucci E, Krithivas K, Dahl DM, Chang G, et al. A polymorphism of the 5 alpha-reductase gene and its association with prostate cancer: a case-control analysis. Cancer Epidemiol Biomarkers Prev 1997; 6 3 ; : 189-92. Kantoff PW, Halabi S, Conaway M, Picus J, Kirshner J, Hars V, Trump D, Winer EP, Vogelzang NJ. Hydrocortisone with or without mitoxantrone in men with hormone-refractory prostate cancer: results of the cancer and leukemia group B 9182 study. J Clin Oncol 1999; 17: 2506. Kavarnos GJ. Fundamentals of Photoinduced Electron Transfer. 1 ed. Aug. 19, 1993 John Wiley & Sons; ISBN: 0471187305 Kennealey GT, Furr BJA. Use of the nonsteroidal anti-androgen casodex in advanced prostatic carcinoma. Urol clin North 18: 99-110, 1991.
Before reconstitution Store at controlled room temperature, 20 to 25C 68 to 77F ; After reconstitution with 0.9% Sodium Chloride Injection, USP Do NOT refrigerate as crystallization may occur Stable for 24 hours if stored at controlled room temperature 20 to 25C 68 to 77F ; Discard unused portion.
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It is well known that the unfolding reactions of different proteins display certain common properties 57, 58 ; . The positive molar heat capacity change associated with the unfolding of a protein, for example, is commonly attributed to the hydrophobic interaction, although other factors may contribute to U C 41, 57 ; . A large positive molar heat capacity change of the unfolding of MM-CK induced by acid, 8.78 kcal mol-1 K-1, at all temperatures examined indicates that hydrophobic interaction is the dominant driving force stabilizing the native structure of this protein. U C P , the thermodynamic term which has been most often scaled to structural feature of a protein 58 ; . The value of U C per amino acid residue for MM-CK, 11.6 0.9 cal K-1 mol res ; -1, is the same order of magnitude as those for monomeric proteins 13.9 0.5 cal K-1 mol res ; -1 58 and homodimeric pea lectin 11.4 cal K-1 mol res ; -1 59 , suggesting that U C P , approximately proportional to the size of a protein. Combining the results from ESI-TOF MS, ITC, fluorescence spectroscopy and glutaraldehyde crosslinking SDS-PAGE we conclude that the acid-induced.
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6. Kreis W. Budman DR, Fetten J et al. Phase I trial of the combination of daily estramustine phosphate and intermittent docetaxel in patients with metastatic hormone-refractory prostate cancer. Ann Oncol 1999, 10- 33-8. Petryiak DP. Macarthur RB, O'Connor J et al. Phase I trial of docetaxel with estramustine in androgen-independent prostate cancer. J Clin Oncol 1999: 17: 958-67. Sinabaldi VJW. Carducci M. Laufer M, Eisenberger M. Preliminary evaluation of a short course of estramustine phosphate and and eszopiclone.
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Note Added in Proof. A recent report presented 19 A. gambiae genes that were inducible by bacterial infection 68 ; . None of these genes were the same as any of the 23 immmune-inducible genes we report here. The strategies were different, however, because ref. 68 used LPS-stimulated hemocyte-like cultured cells, and we used LPS-stimulated whole mosquitoes. Thus, the cells used in ref. 68 represented a subset of the immune-responsive cells in whole mosquitoes and may not have included mRNAs expressed in other cell types, whereas cells related to those in ref. 68 and their cell-specific transcripts may be relatively rare in vivo and could therefore be rare in our enriched library made from wholemosquito mRNA. However, the lack of overlap in the two collections also emphasizes the point that the insect immune response is complex and involves a large number of genes. We thank John Seed, Edge Biosystems, for helpful advice on properties of the binding matrices used. We acknowledge support to K.D.V. by the U. S. Public Health Service National Institutes of Health R01AI42361 ; and the United Nations Development Program World Bank World Health Organization Special Program for Research and Training in Tropical Diseases 970435 and exenatide.
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1. Brady R, Gal AE, Bradley RM, Martensson E, Warshaw AL, Laster L 1967 ; N Engl J Med 276: 11631167. 2. Desnick R, Ioannou YA, Eng CM 2001 ; in The Metabolic and Molecular Bases of Inherited Disease, ed Charles R, Scriver, Arthur L, Beaudet WS, Sly DV McGrawHill, New York ; , 8th Ed, pp 37333774. 3. Mitsias P, Levine SR 1996 ; Ann Neurol 40: 817. 4. Moore D, Ye F, Schiffmann R, Butman JA 2003 ; AJNR 24: 10961101. 5. Moore D, Altarescu G, Ling GSF, Jeffries N, Frei K, Weibel T, Charria-Ortiz G, Ferri R, Brady RO, Schiffmann R 2002 ; Stroke 33: 525531. 6. Moore DF, Scott LJC, Gladwin MT, Altarescu G, Kaneski C, Suzuki K, Pease-Fye M, Ferri R, Brady RO, Herscovitch P, Schiffmann R 2001 ; Circulation 104: 15061512. 7. Moore DF, Ye F, Brennan ML, Gupta S, Barshop BA, Steiner RD, Rhead WJ, Brady RO, Hazen SL, Schiffmann R 2004 ; J Magn Reson Imaging 20: 674683. 8. Moore DF, Pursley R, Altarescu G, Schiffmann R, Dimitriadis E 2001 ; in 14th IEEE Conference on Computer-Based Medical Systems, eds Thomas G, Long R IEEE, Bethesda, MD ; , pp 216221. 9. Schiffmann R, Kopp J, Austin H, Sabnis, Sharda, Moore DF, Weibel T, Balow J, Brady RO 2001 ; J Med Assoc 285: 27432749. 10. Bodary PF, Shen Y, Vargas FB, Bi X, Ostenso KA, Gu S, Shayman JA, Eitzman DT 2005 ; Circulation 111: 629632. 11. Ohshima T, Schiffmann R, Murray GJ, Kopp J, Quirk JM, Stahl S, Chan CC, Zerfas P, Tao-Cheng JH, Ward JM, Brady RO, Kulkarni AB 1999 ; Proc Natl Acad Sci USA 96: 64236427. 12. Shen Y, Bodary PF, Vargas FB, Homeister JW, Gordon D, Osteno KA, Shayman JA, Eitzman DT 2006 ; Stroke 37: 11061108. 13. Eitzman D, Bodary PF, Shen KY, Khairallah CG, Wild SR, Abe A, ShafferHartman J, Shayman JA 2003 ; J Soc Nephrol 14: 298302. 14. Roepman R, Bernoud-Hubac N, Schick DE, Maugeri A, Berger W, Ropers HH, Cremers FP, Ferreira PA 2000 ; Hum Mol Genet 9: 20952105. 15. Castagnet P, Mavlyutov T, Cai Y, Zhong F, Ferreira P 2003 ; Hum Mol Genet 12: 18471863. 16. Ferreira PA 2005 ; Hum Mol Genet 14: R259R267. 17. Lu X, Guruju M, Oswald J, Ferreira PA 2005 ; Hum Mol Genet 14: 13271340. 18. Browne MW 1984 ; Br J Math Stat Psychol 37: 6283. 19. Faraci F, Didion SP 2004 ; Arterioscler Throm Vasc Biol 24: 13671373. 20. Schafer J, Stimmer K, 2004 ; Bioinformatics 1: 114. 21. Halpern J, Pearl J 2001 ; in Proceedings of 17th Conference on Unceratinty in Artificial Intelligence Morgan Kauffmann, San Francisco, CA ; , pp 194202.
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